Brand Overview
- Treatments: Estrogen therapy, progesterone therapy, testosterone therapy, non-hormonal treatment
- Forms: Cream, pill, patch, vaginal ring
- Works best for: Individuals experiencing symptoms related to perimenopause or menopause
- Cost: $50 for blood work, $200 for video consultation, medication cost is additional
Science & Humans (formerly ONMEN) is a telemedicine platform that offers a bioidentical hormone replacement therapy (bHRT) program, which includes blood work, video consultations with a medical professional, and medication delivery. The platform offers estrogen therapy, progesterone therapy, and testosterone therapy, which all help alleviate menopause and perimenopause symptoms. In addition, they offer a non-hormonal treatment called venlafaxine, a selective serotonin and norepinephrine reuptake inhibitor (SNRI), that is used to help relieve hot flashes.
With a wide range of customizable treatments and quarterly follow-ups with bHRT-certified clinicians, we recommend Science & Humans as a platform for people who may benefit from menopause treatment. While individuals should discuss the potential side effects of bHRT and venlafaxine with their physicians, these treatments can be effective solutions for some individuals.
Read on for a complete overview of Science & Humans’ bHRT program, including a detailed rundown of their treatment options, key benefits, side effects, and more.
While on the pricier side compared to other telemedicine platforms that offer menopause treatment, Science & Humans appears to be one of the most thorough when it comes to tracking and monitoring symptoms, progress, and overall well being. The company conducts extensive blood work prior to beginning treatment, as well as quarterly follow up blood work and video consultations with a healthcare provider to ensure that the treatment is working appropriately.
Science & Humans bHRT Pros & Cons
Pros
- Offers a comprehensive range of personalized treatments, including estrogen, progesterone, testosterone, and non-hormonal treatment
- Personalized and compounded dosages ensure that each individual receives the appropriate amount for their specific needs
- Quarterly follow-ups with bHRT-certified clinicians help ensure that you achieve your desired results
- Detailed blood testing helps ensure that you get the best prescription treatment for your needs and body chemistry
Cons
- There may be potential side effects associated with bHRT, which individuals should discuss with their healthcare providers
- The personalized approach and compounded medications may be more expensive than standardized hormone therapies
What Is Science & Humans Canada?
Formerly called ONMEN, Science & Humans is a Canadian telemedicine platform that used to be exclusively dedicated to lifestyle treatments for people assigned male at birth. Now, along with weight loss, anti-aging, hair loss, and sexual wellness offerings, it provides comprehensive bioidentical hormone replacement therapy and non-hormonal treatment for managing symptoms of perimenopause and menopause.
Science & Humans’ approach is centred around hormonal health and its importance to overall wellness and longevity.
Benefits: Do Science & Humans' bHRT Treatments Work for Menopause Care?
Bioidentical hormone therapy is different from other forms of hormone replacement therapy because it uses hormones that are chemically identical to those that your body naturally creates. It is considered one of the best available treatments for individuals who don’t naturally produce enough hormones or have naturally declining hormone levels due to age.
Menopause is defined as the stage 12 months after a person’s last period. In this stage, the ovaries stop producing estrogen and progesterone. This age-related drop in hormones can cause a variety of symptoms, including:
- Mood changes
- Changes in sexual desire
- Trouble concentrating
- Headaches
- Night sweats
- Hot flashes
- Vaginal dryness
- Vaginal pain during intercourse
Science & Humans offers 4 types of bHRT, including estrogen therapy, progesterone therapy, testosterone therapy, and a combination therapy, to restore the hormones that decreased during menopause. In addition, they offer a non-hormonal treatment option that helps with hot flashes.
Related reading: Best Libido Gummies for Women
Benefits of Science & Humans Estrogen Therapy
Science & Humans estrogen therapy is available as a cream, ring, pill, or patch.
To use:
- Apply the cream once daily
- Take the pill once daily
- Apply the patch twice weekly
- Insert a new ring once every three months
It’s an effective therapy for vaginal atrophy, which describes symptoms such as dryness, itching, burning while urinating, and pain or spotting during intercourse. It’s also effective for vasomotor symptoms, such as hot flashes and night sweats. Individuals typically notice results within three to four weeks.
Research shows that systemic HRT, including a patch or pill, with estrogen eliminates symptoms of vaginal atrophy in 75% of cases, while local estrogen HRT cream does so for 80% to 90% of cases. Vaginal rings can be considered local and systemic depending on the dose.
Frequent and persistent hot flashes and night sweats are associated with an increased risk of cardiovascular disease. However, beginning estrogen hormone therapy before the age of 60 and within 10 years of menopause onset may have a protective effect against cardiovascular disease, in some cases.
Benefits of Science & Humans Progesterone Therapy
Science & Humans progesterone therapy is available as a cream or in pill form.
To use:
- Apply the cream once daily
- Take the pill once daily
Progesterone therapy can help with symptoms of perimenopause, including night sweats. It can also be taken with estrogen HRT to decrease the risk of endometrial cancer. Typically, individuals notice some symptom alleviation within three to four weeks.
In a 2023 study, individuals experienced decreased night sweats, improved sleep quality, and reduced perimenopause-related life interference while taking progesterone.
Benefits of Science and Humans TRT
Science & Humans testosterone therapy is available as a cream and is applied once daily. Testosterone therapy can help improve libido, bone density, muscle mass, and cognitive health in individuals experiencing perimenopause or menopause. Some individuals notice improved symptoms within three to four weeks.
Related reading: Science and Humans TRT Review
Science & Humans Combination Therapy
Science & Humans combination therapy is a custom-formula body cream that includes estrogen, progesterone, and testosterone. It is applied once daily.
Combination creams may help with symptoms of menopause and perimenopause while reducing the risks associated with estrogen-only therapy, including hyperplasia (uterus lining is abnormally thick) and endometrial cancer. Results are typically seen within three to four weeks.
Science & Humans Non-Hormonal Treatment
Science & Humans non-hormonal treatment is an oral pill called venlafaxine, an SNRI used to manage hot flashes. It is taken once a day, with individuals noticing results in about three to four weeks. Individuals who are at high risk for certain conditions, such as cardiovascular disease or cancer may be prescribed non-hormonal treatment options instead of hormonal ones.
Why We Recommend Science & Humans for Menopause Treatment
We recommend Science & Humans as a convenient way to get menopause treatment from home. With a comprehensive range of treatment options, customized treatment plans from bHRT-certified physicians, fast home delivery, and follow-up consults for ongoing care, it’s a safe and effective way to manage menopause symptoms for some individuals.
Comprehensive Blood Work
The first step in receiving bHRT for menopause through Science & Humans is to complete blood work. This platform uses an extensive blood panel that checks for 19 health and hormone markers, including TSH, free T3/T4, LH/FSH, prolactin, and DHEA. After signing up, you’ll receive a blood work requisition via email within 24 hours, which you can take to receive blood testing in person.
Personalized, Scientifically-Proven Treatments
Science & Humans provides personalized treatments, including customized dosages and lifestyle recommendations, based on your blood test results. A bHRT-certified clinician will determine your plan during the initial video consultation. With a variety of scientifically proven treatments available, your clinician can prescribe a form of bHRT that closely fits your needs, if appropriate.
Regular Follow-Ups With bHRT-Certified Clinicians
You’ll have a follow-up video consultation every 3 months to monitor your progress. This gives your clinician the ability to make adjustments as needed if you’re not experiencing your desired results, or if you experience side effects.
Additional Treatments for Menopause Care
Menopause can have an impact on an individual’s weight and hair growth. Science & Humans offers a variety of weight loss/management treatment options, including a CGM device to monitor blood sugar, GLP-1 medications, and Contrave (naltrexone with bupropion). For hair growth, they offer products containing finasteride and minoxidil, two clinically proven products for managing certain hair loss conditions.
Safety and Side Effects of Science & Humans Menopause Treatments
The primary safety concern surrounding bHRT for menopause is breast cancer risk. Hormone replacement therapy was linked to an increased risk of breast cancer by clinical research in the early 2000s. However, further research has revealed that this link is complex and depends not only on the individual, but also on the form of bHRT. The North American Menopause Society has reported that for healthy people under age 60 or within 10 years of menopause onset, the benefits of estrogen therapy outweigh the risks.
Your bHRT-certified clinician from Science & Humans may prescribe, if appropriate, a Health Canada-authorized treatment that’s safe for you based on your blood test results and medical history. Individuals who have previously had breast cancer or other conditions that are considered at a heightened risk usually aren’t advised to start HRT.
Side Effects
Additionally, bHRT and non-hormonal treatment can trigger side effects in some individuals.
Side effects of estrogen and/or progesterone therapy can include:
- Headaches
- Nausea
- Breast tenderness or pain
- Mood fluctuations
- Mild skin rash or itchiness
- Diarrhea
- Hair loss
- Leg cramps
- Dizziness
Side effects of TRT for menopause can include:
- Acne
- Hair loss
- Increased (unwanted) hair growth
- Voice changes
Side effects of venlafaxine may include:
- Fatigue
- Stomach pain
- Headache
- Nausea
- Sexual concerns, such as delayed orgasm or decreased sex drive
- Sweating
- Loss of appetite
- Dizziness
- Dry mouth
- Flushing
When to Seek Emergency Medical Care
If you experience vaginal bleeding, severe rash, hives, difficulty breathing, irregular heartbeat, hallucinations, or any other severe side effects, seek urgent medical care.
Compare the Best Online Menopause Treatment Program
We compared Science & Humans to other telemedicine platforms offering treatment for menopause, including Winona, Jill Health, and Maple, to help you better understand which platform may best suit your needs.
Science & Humans vs. Winona vs. Jill Health vs. Maple | Science & Humans | Winona | Jill Health | Maple |
|---|---|---|---|---|
| Approach | bHRT and non-bHRT treatments | bHRT | Supplements and prescription meds | Hormone therapy and OTC menopause treatments |
| Types of treatments | Estrogen therapy Progesterone therapy Testosterone therapy Venlafaxine | Estrogen therapy Progesterone therapy DHEA | Birth control pills Hair loss (minoxidil) Weight loss | Low-dose antidepressants Vaginal estrogen Clonidine Gabapentin Osteoporosis medications |
| Multiple forms of treatments? | ✅ | ✅ | ✅ | ✅ |
| Price | $50 for blood work $200 for follow-ups every 3 months Medication cost is additional | Depending upon form: Estrogen therapy: $49 to $149/month Progesterone therapy: $39 to $79/month DHEA: $24 for 3 months | Depending upon treatments: Birth control pills: $20/month Hair loss: $30 to $110 Weight loss: $300 | Weekdays: $69/visit Weekends: $79/visit Overnight: $99/visit |
| Blood work required? | ✅ | ❌ | ❌ | ❌ |
| Personalized treatments? | ✅ | ✅ | ❌ | ✅ |
| Compounded treatments? | ✅ | ✅ | ❌ | ❌ |
| bHRT certified clinicians? | ✅ | ✅ | ❌ | ✅ |
| Accepts insurance? | ✅ | ✅ Covered by some private insurance | ✅ | ✅ |
| At-home delivery? | ✅ | ✅ | ✅ | ✅ |
| Website |
Our Experience With Science & Humans bHRT
Science & Humans has a user-friendly interface with detailed information about every step of the process. With clearly displayed pricing and upfront info about each available treatment, we felt confident going into the sign-up process. Plus, with customer service through a live chat available, we were able to receive prompt answers to all of our questions.
Science & Humans Reviews From Their Customers
Science & Humans has earned hundreds of positive customer reviews across the web, with a 4.6-star average on TrustPilot. Customers love that the S&H team is friendly and professional, with a straightforward signup process. While some customers experienced confusion or complications while having their prescriptions filled by the pharmacy, they noted that the customer service team helped them resolve the issue.
The Verdict: Is Science & Humans bHRT Legit for Menopause Care?
Science & Humans is ideal for individuals looking for a convenient way to manage menopause or perimenopause symptoms.
With a broad range of treatment options and forms, including pills, patches, creams, and rings, S&H can suit a variety of needs.
We love that Science and Humans Canada provides a detailed blood panel to begin the bHRT program and conducts telehealth and blood panel follow ups on a quarterly basis. This gives your clinician the information required to create a detailed, personalized treatment plan and adjust it throughout the treatment process.
While S&H’s personalized approach may be more expensive than standard bHRT options, it’s covered by most standard drug plans, making it a fitting choice for many people wanting to reduce or better manage their menopause symptoms.
Frequently Asked Questions (FAQs)
How does Science & Humans blood testing process work?
Science & Humans will send you a blood work requisition form within 24 hours of signing up. You can take this form to a clinic in your area to complete the blood panel, then send the results to Science & Humans for your clinician to review.
Does Science & Humans accept insurance?
Yes, Science & Humans accepts insurance. The platform directly bills insurance for your medications, and most of their prescription treatments are covered under a standard drug plan.
Is HRT covered in Canada?
HRT through Science & Humans in Canada is covered under most standard drug plans.
Does HRT lower life expectancy?
HRT doesn’t lower life expectancy, according to clinical research.
Is HRT covered by OHIP?
HRT is covered by OHIP with certain restrictions.
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Methodology
We conducted extensive research to evaluate the pricing, effectiveness, accessibility, overall quality, customer support, and useability of Science & Humans bHRT program, which also included examining multiple bHRT telemedicine programs. To determine overall value, we evaluated cost, usability, treatment options, and personalization.
Other factors we investigated prior to choosing the best menopause treatment program included convenience, discounts, customer service, ongoing access to clinicians, health insurance, and any free resources offered. For the best menopause treatment program, Science & Humans stood out for its wide range of customizable treatments, and ongoing, personalized care for individuals going through menopause.
| Review Process | Key Metrics | Weighting |
|---|---|---|
| Sign up online | – ease to complete intake form – affordability – upfront commitment or subscription required? – money back guarantee or refund policy? | 0.5 |
| Vitual consult with provider / determine eligibility | – ease to get appointment to determine eligibility – need to leave house for labs or other in-person care? | 1 |
| Shipping + unboxing | – shipping cost – time from order to treatment delivery – discreet packaging to maintain privacy | 0.5 |
| Test + journal for 1-3 months | – ease of application – transition into habitual use – taste / smell / feel / pain | 1.5 |
| Results after 3 months of use | – efficacy / results – lack of side effects – ease of refill / reordering – quality of ongoing clinical support – responsive customer support – willingness to recommend to a friend | 1.5 |
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